Effect of spinal double hemisections on amygdala-kindled convulsions by Li ChК»en

Cover of: Effect of spinal double hemisections on amygdala-kindled convulsions | Li ChК»en

Published by National Library of Canada in Ottawa .

Written in English

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Edition Notes

Thesis (M.Sc.)--University of Toronto, 1993.

Book details

SeriesCanadian theses = Thèses canadiennes
The Physical Object
Pagination2 microfiches : negative.
ID Numbers
Open LibraryOL19537135M
ISBN 100315870036

Download Effect of spinal double hemisections on amygdala-kindled convulsions

Anxiolytic effects of kindling role of anatomical location of the kindling electrode in response to kindling of the right basolateral amygdala. Brain Res.44– /es ; Adamec R. E., Morgan H. The effect of kindling of different nuclei Cited by:   A disruption in cognitive function and induction of astrogliosis in the brain have been reported as neurotoxic effects of ′-iminodipropionitrile (I Cited by: 5.

Convulsions and Temporary Hemiparesis following Spinal Anesthesia in a Child with Moyamoya Disease Anesthesiology 12Vol, doi: Anesthesiology 12 Cited by: 8. EXPERIMENTAL NEUROL () Effects of Phenytoin, Carbamazepine, and Clonazepam on Cortex- and Amygdala-Evoked Potentials PENNY S.

ALBRIGHT AND W. BURNHAM' Department of Pharmacology, University of Toronto, Toronto, Ontario M5S 1A8, Canada Received Octo Multiple doses of phenytoin, carbamazepine, and clonazepam were tested against single- and double Cited by: 4.

The behavioral depression induced by an amygdala-kindled seizure was studied in fully kindled rats, with or without prior injection of fentanyl ( mg/kg, s.c.). convulsive seizures have.

In contrast to dextromethorphan, dextrorphan induced 4~ TABLE 1 Effect of acute treatment of amygdala-kindled rats with dextromethorphan or dextrorphan. Control recordings of seizure parameters were made days prior to drug injection by using the same vehicle and the same time between i.p. injection and amygdala stimulation as in the.

The anti-seizure effects of progesterone family compounds have long been known. Over the years, however, most studies have focused on progesterone and on its secondary metabolite allopregnanolone. Spinal curvature in the coronal plane is caused by unbalanced anatomy and growth potential of the two sides of the spine.

Unlike idiopathic scoliosis, congenital scoliosis progresses in up to 75 % of patients and most often affects the thoracic spine (thoracolumbar scoliosis is the second most common).

Initially after spinal cord damage there is a period of spinal shock when your reflexes are not present. These reflexes can return anytime up to 3 months, usually between 1 to 6 weeks. Until your reflexes return there is a ‘flaccid’ effect. The loss of spinal reflexes results in flaccid paralysis below the level of your injury.

This also. knowledge of the hypothetical spinal cord lesion is the first step toward interpreting the more confusing array of signs and symptoms encountered in patients. It should also be noted that when a spinal cord lesion is localized to a certain level, this level refers to the spinal Effect of spinal double hemisections on amygdala-kindled convulsions book itself, and not the surrounding bony vertebral column.

Van Buren JM. Sensory, Motor and autonimi effects of mesial temporal stimulation in man. J Neurosurg. Velasco Al, Velasco F, Velasco M, Trejo D, Castro G, Carrillo-Ruiz JD.

Electrical situation of the hippocampal epileptic foci for seizure control: A double-blind, long-term follow-up study. Epilepsia.

Download Citation | Gliomatosis of the spinal cord in a cat: A case report | Gliomatosis cerebri situated in the thoracolumbar and lumbosacral segments of the spinal cord was diagnosed in a.

The effects of the neurotoxins on seizure sensitivity in fully kindled rats were assessed, as described earlier, by measuring after-discharge threshold and the other three parameters of the amygdala-kindled seizures 3, 7, 10, 15, 21, 35, 50, and 64 days after the infusion.

A role has not been demonstrated in experimental animals for the corticospinal tract, consistent with the view that the brainstem is the critical site for the generation of convulsions.

In fact, bilateral spinal hemisections at different levels do not prevent gener- alized kindled convulsions in the rat (Ninchoji et aL, ). References [1] Albright, P.S. and Bruni, J., Effects of carbamazepine and its epoxide metabolite on amygdala-kindled seizures in rats, Neu- rology, 34 () [2] Albright, P.S.

and Burnham, W.M., Development of a new pharmacological seizure model: effects of anticonvulsants on cortical- and amygdala-kindled seizures in the rat.

PTZ and amygdala kindling procedures are the two widely used animal models to screen anti-epileptic drugs (Dhir, ).

In one study with the electrical kindled animals (amygdala electrical. Effect of BRV and LEV on seizure parameters in fully amygdala‐kindled mouse (A) and rat (B). The behavioral effect of stimulation was measured by a seizure severity score, according to the scale of Racine, and the electroencephalographic effect was determined by measuring the duration of the stimulation‐induced afterdischarge.

Last Updated on Sun, 12 Aug | Spinal Cord. One of the major differences between the amygdala and the other parts of the basal ganglia is that the amygdala is not a homogeneous nuclear structure but is composed of different component parts.

These are. The effect of amygdala kindling on neuronal firing patterns in the lateral thalamus in the GAERS model of absence epilepsy.

Nihan Çarçak. GAERS did not progress beyond class II seizures, with a matched number of kindling stimulations, and the thalamic neuronal firing alterations observed in. 45 Safranal, an active monoterpene aldehyde in Crocus sativus L., had beneficial effect on PTZ-induced convulsions in mice by interacting with GABA A -benzodiazepine receptor complex.

46, INTRODUCTION. Corticospinal tract (CST) innervation takes place during a critical period of spinal cord maturation and is thought to contribute to a reorganization of spinal circuitry, including the proprioceptive sensorimotor reflex circuit, thereby refining locomotor control (Clowry, ).Innervation of the embryonic spinal cord by higher brain centers is one of the final phases of spinal.

Spinal cords from rats that received T9 DF lesions were sectioned in the sagittal plane, whereas spinal cords from rats that received C5 hemisections were sectioned in the horizontal plane.

Sagittal sections allow a more precise assessment of the depth of the T9 DF lesions and the degree to which the lesions destroy the main CST in the dorsal. Indeed, low frequency stimulation (1 Hz for 15 minutes) after kindling of the amygdala and hippocampus inhibited the development and expression of amygdala-kindled seizures (Weiss et al.,), suppressed the afterdischarge duration (Velisek et al., ) and increased the afterdischarge threshold (Bragin et al., ).

In STR-induced seizure in rats, H3R antagonist 4 with the most promising effect in MES- and PTZ-induced seizures failed to provide any appreciable protection in STR-induced seizure when compared with the saline-treated group after 30 min of observation.

Audio Books & Poetry Community Audio Computers, Technology and Science Music, Arts & Culture News & Public Affairs Non-English Audio Spirituality & Religion. Full text of "Lectures on the localisation of cerebral and spinal diseases: delivered at the Faculty of Medicine of Paris".

Vigabatrin tended to have a short-lived proconvulsant effect in amygdala-kindled animals followed by a prolonged decrease in susceptibility to the motor component of these seizures.

The drug was also anticonvulsant in animals with a genetic susceptibility, including audiogenic seizures and a model of febrile seizures in photoepileptic chicks.

Audio Books & Poetry Community Audio Computers, Technology and Science Music, Arts & Culture News & Public Affairs Non-English Audio Spirituality & Religion. Full text of "Lectures on the localisation of cerebral and spinal diseases.

Delivered at the Faculty of medicine of Paris". Spinal cord injury (SCI) produces a wide variety of changes in systemic physiology that can lead to complications over time. Patients with chronic spinal cord dysfunction often require anesthesia for urologic, orthopedic, and plastic surgical procedures.

Epilepsy is a chronic neurological disorder, which presents with various forms of seizures. Traditional treatments, including medication using antiepileptic drugs, remain the treatment of choice for epilepsy.

Recent development in surgical techniques and approaches has improved treatment outcomes. However, several epileptic patients still suffer from intractable seizures despite the advent of. Carbamazepine is an analgesic, anti-epileptic agent that is FDA approved for the treatment of epilepsy, trigeminal neuralgia.

It appears to act by reducing polysynaptic responses and. Audio Books & Poetry Computers, Technology and Science Music, Arts & Culture News & Public Affairs Non-English Audio Spirituality & Religion Clash Planet. Librivox Free Audiobook.

Full text of "Lectures on the Localisation of Cerebral and Spinal Diseases: Delivered at the Faculty of. This diagram, which is the same as Fig highlights a functional portion of the limbic system — the amygdala and its pathways, the stria terminalis and the ventral amygdalofugal pathway.

The septal region and functionally connected portions of the midbrain and medulla are also marked. Isovaleramide decreased the mean seizure score and the afterdischarge duration in amygdala-kindled rats, showing that it exerts anticonvulsant activity against both focal and secondarily generalized seizures.

FIG. 6 illustrates the antiepileptogenesis effect of a daily mg/kg p.o. dose of isovaleramide compared to controls. Isovaleramide. Effect of spinal cord lesions and bath partition on combined 5-HT/NMA-induced rhythms.

Application of 5-HT combined with NMA (or DHK) has proven to be a useful means of establishing locomotor-like patterns in the in vitro neonatal rat whole spinal cord preparation (e.g., Cowley and Schmidt a; Kjaerulff et al.

; Sqalli-Houssaini et al. THE KINDLING MODEL OF EPILEPSY. Kindling is the most widely studied animal model of complex partial epilepsy. In this model, an initially subconvulsive stimulus is periodically administered to the brain of an animal (most often a rodent); over time, this same stimulus results in intense limbic and clonic motor seizures.

22–24 Sevillano first described this effect indiscovering that. Seizures. Several conditions that can cause hemiplegia may also result in seizures and strokes that impact the hemiplegic’s health.

Seizures, or abnormal electrochemical activity in the brain, can cause full-body muscle spasms, difficulty breathing, and changes in mood or cognition. A case of spinal epidural hemangioma is presented. The rarity of this lesion in comparison with the more frequent vertebral hemangiomas with secondary extension to the epidural space is emphasized.

The special features of this case are noted: the acute clinical onset, the visualization by means of the spinal angiography, and the unusual cervical level.

CONCLUSION: According to literature review and our patient's outcome, pregnancy may induce neurologic symptoms and signs in silent spinal hemangiomas. The way of management is decided by whether the neurologic deficits depend on the deformity caused by hemangioma or some other factors including vascular insufficiency.

Degenerative conditions of the spine such as spinal arthritis, occur as part of the normal aging process. Nearly everyone experiences some degeneration of spinal discs or spinal joints by age However, in some individuals, these degenerative changes are more advanced than is typical for their age.

Vertebral hemangiomas are relatively common abnormalities. They have been found in percent of spines at autopsy and in percent of people over the age of 60 years1. However, neurologic sym.

spinal cord (spinal cats) can stand and step when sensory input is provided to the lumbosacral pattern generator circuitry.7–9 Spinal cats can learn to stand, fully supporting their hindquarters, and to step at a range of speeds and load-bearing levels with task-specific training.

Adult.Intramedullary spinal cord hemorrhage (hematomyelia). Rev Neurol Dis. ; 6(2):E (ISSN: ) Leep Hunderfund AN; Wijdicks EF. Intramedullary spinal cord hemorrhage (hematomyelia) is an uncommon cause of myelopathy and can present in an acute, subacute, stepwise, or chronic fashion.spinal accessory nucleus lateral motor cell column of upper and lower limbs phrenic nucleus.

spinal accessor nucleus location. C1-C6. lateral motor cell column to upper limb location. C5-T1. phrenic nucleus location. C3-C5. lateral motor cell column to lower limb .

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